| Data | Frequency |
|---|---|
| Total number of samples in GTEx (ver. 2.0) | 9,247 |
| Number of analyzed samples (24 tissues) | 4,441 |
| Number of utilized samples (mean of alignment 93.4%) | 3,548 |
| Gastrointestinal tissue (Stomach, Colon - Transverse, Sigmoid ) | 544 |
| Cardiac tissue (Left ventricle, Atrial appendage) | 411 |
| Muscle - Skeletal | 366 |
| Whole Blood | 291 |
| Thyroid | 272 |
| Lung | 225 |
| Pancreas | 183 |
| Liver | 134 |
| Brain - Basal ganglia (Brain - Caudate, Putamen, Nucleus accumbens) | 294 |
| Brain - Cortical areas (Brain - Cortex, Frontal Cortex (BA9), Anterior cingulate cortex (BA24)) | 287 |
| Brain - Cerebellum (Brain - Cerebellar Hemisphere, Cerebellum) | 216 |
| Brain - Diencephalon & Limbic System (Brain - Amygdala, Hippocampus, Hypothalamus) | 206 |
| Brain - Central & Medulla (Brain - Substantia nigra, Spinal cord (cervical c-1)) | 119 |
| Number of E3 ligases | 599 |
| Tissue-specific E3 ligases (FDR of p-value < 0.05) b | 599 |
| Number of associated E3 ligase-target gene (FDR of p-value < 0.05) c | 2,983,630 |
| Gastrointestinal organ (Stomach, Colon - Transverse, Sigmoid) | 206,219 |
| Cardiac organ (Left ventricle, Atrial appendage) | 226,292 |
| Whole Blood | 171,506 |
| Muscle – Skeletal | 244,575 |
| Thyroid | 265,911 |
| Pancreas | 179,098 |
| Lung | 238,878 |
| Brain (Basal ganglia) | 240,380 |
| Brain (Cerebellum) | 233,063 |
| Brain (Cortical areas) | 187,433 |
| Brain (Central & Medulla) | 189,115 |
| Brain (Diencephalon & Limbic System) | 229,448 |
| Liver | 204,300 |
| Whole tissue | 167,412 |
a Samples were filtered out using the overall alignment rate of Hisat2 (<80%). b Tissue-specificity of a gene was determined by Mann-Whitney U test for transcriptional expressions of each gene across tissues. c The p-value of mutual information score was calculated in 100 bootstrap consolidation for indicating
For ELiAH v1.0 https://pubmed.ncbi.nlm.nih.gov/39395186/